Detalle Publicación

ARTÍCULO

A single-center experience with third and fourth kidney transplants and second kidney transplant after pancreas-kidney transplant: Surgical aspects and outcomes

Autores: Segura, J. S. (Autor de correspondencia); Rosa, J. V. ; Gomez, E. G. ; Navarra Cabello, M. D.; Robles-Garcia, J. E.; Rodríguez-Benot, A.; Robles García, José Enrique; Requena-Tapia, M. J.; Campos-Hernandez, J. P.
Título de la revista: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
ISSN: 1304-0855
Volumen: 18
Número: 2
Páginas: 149 - 152
Fecha de publicación: 2020
Resumen:
Objectives: Overall, 25% to 33% of patients on kidney transplant wait lists present with prior graft loss. In addition, the number of patients who require a retransplant seems to be increasing. Here, we describe our experience with patients who had a second kidney transplant after a previous pancreas-kidney transplant or a third or fourth kidney transplant. We focused specifically on the technical aspects and outcomes related to this patient group. Materials and Methods: A single-center retrospective study was performed. The cohort included 15 patients > 18 years old who had received a second kidney graft after pancreas-kidney transplant or a second or greater kidney graft between 2013 and 2019. Results: Median age of recipients was 45 years (range, 20-58 y). In 10 patients, the transperitoneal approach was selected. In 5 patients, the retroperitoneal heterotopic kidney retransplant technique was used. Early surgical complications (<= 30 days posttransplant) were reported in 4 patients. Three patients had late ureteral stenosis (> 90 days posttransplant). All grafts were functioning at time of patient discharge. Mean creatinine level was 2.69 mg/dL (range, 1.23-6.26 mg/dL).The 1-year and 2-year graft survival rates were 85% and 75%, respectively. No grafts were lost because of surgical complications. Conclusions: Retransplant of a second graft after pancreas-kidney transplant or retransplant of a third or fourth renal graft is challenging but feasible, with evidence of reasonably positive outcomes after retransplant.
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