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ARTÍCULO

COBRA methods and metabolic drug targets in cancer

Autores: Apaolaza Emparanza, Iñigo; San José Enériz, Edurne; Aguirre Ena, Xabier; Prosper Cardoso, Felipe; Planes Pedreño, Francisco Javier (Autor de correspondencia)
Título de la revista: MOLECULAR AND CELLULAR ONCOLOGY
ISSN: 2372-3556
Volumen: 30
Número: 5
Páginas: e1389672.
Fecha de publicación: 2018
Resumen:
The identification of therapeutic strategies exploiting the metabolic alterations of malignant cells is a relevant area in cancer research. Here, we discuss a novel computational method, based on the COBRA (COnstraint-Based Reconstruction and Analysis) framework for metabolic networks, to perform this task. Current and future steps are presented.
DOI: https://doi.org/10.1080/23723556.2017.1389672
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