Research
BACTERIAL DISEASES
These are caused by bacteria, microscopic single-celled organisms made up of prokaryotic cells. They are the most common infectious diseases ranging from minor skin infections to bubonic plague and tuberculosis. Bacteria cause disease by secreting or excreting toxins, by producing toxins internally, or by inducing sensitivity to their antigenic properties.
PARASITIC DISEASES
These are diseases caused by protozoa, worms or arthropods. They can be acquired through food, contaminated water, insect bites or by contact sexually. These diseases cause great damage in tropical and subtropical regions. Factors associated with these parasitic infections include: faecal contamination of soil or water, environmental conditions conducive to the reproduction of certain parasites, poor hygiene, dietary habits, migration or immunosuppression, among others.
VIRAL DISEASES
The Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AIDS), a human disease characterised by low levels of CD4 lymphocytes associated with development opportunistic infections and some cancers.
PATHOGEN IMMUNOLOGY
One of the mechanisms used by pathogens to persist in humans is to modulate the host's immune response. Therefore, understanding these mechanisms is essential both to understand the transmission and progression of the disease they cause, and to study new therapeutic targets in the fight against these pathogens. In this section, we characterise the immune response in animal models that chronically harbour the pathogen, as well as after the administration of possible candidate treatments.
Collaborating with ISTUN
Centres, by geographical location
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Instituto Carlos III Majalahonda - Madrid
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University Institute of Tropical Diseases and Public Health of the Canary Islands
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laboratory de Parasitología Lopez Neyra (Granada, Spain)
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Animal Health Unit, CITA. Government of Aragon, Zaragoza
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Institute of Agrobiotechnology ( CSIC-UPNA-Government of Navarre) Navarre
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Barcelona Institute for Global Health (ISGlobal) (Spain)
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World Health Organisation - Geneva (Switzerland)
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Institut Pasteur - Paris (France)
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ICP Institut de Pathologie Cellulaire Institut Christian de Duve- Louvain (Belgium)
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Institut de Recherche pour le Développement-Université Paul Sabatier PharmaDEV. Faculty of Pharmaceutical Sciences. Toulouse (France)
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Laboratory of Biotechnology. National Institute of Chemistry, Slovenia
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GDR Biodefence, Centre d'Immunologie de Marseille-Luminy, France
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Laboratorie d'Immunologie et Microbiologie, Notre Dame de la Paix, Namur -Belgium
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Palestine Polytechnic University, Palestinian Authority, Via-Israel
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Royal (Dick) School of Veterinary Studies, University of Edinburgh, United Kingdom
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Biological Chemistry and Drug Discovery. University of Dundee, Scotland
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University of Trieste. Italy
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International Livestock Research Institute, Nairobi, Kenya
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Nigerian Field and Epidemiology and Laboratory Training Program, Nigeria.
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Institut des Régions Arides (IRA), Tunisia
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Ifakara Health Centre (Tanzania)
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Federal University of Pernambuco - Brazil
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Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz (Fiocruz), Salvador, Bahia, Brazil
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group of Malaria. University of Antioquia, Medellin, Colombia.
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National University of Colombia. Bogotá (Colombia)
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Tropical Diseases Research Programme (PIET), School of Veterinary Medicine, National University, Costa Rica.
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department de fármacos. Federal University of Rio de Janeiro. Brazil
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group of medicinal chemistry. University of the Republic of Uruguay. Uruguay
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department of Tropical Medicine. National University of Asunción. Paraguay
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Laboratorios Silanes (Mexico)
