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The disease

Brucellosis is a disease caused by bacteria of the genus Brucella. It mainly affects cattle, pigs, goats, sheep and dogs. It is transmitted to humans via contact directly to sick animals, through wounds and mucous membranes, or indirectly, by ingestion of animal products and inhalation. In animals it induces abortions, reduces fertility and decreases milk production. In humans it causes repeated episodes of high fever - Malta fever - and other symptoms such as headache, joint pain, fatigue and depression.

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Brucellosis is one of the most widespread zoonoses in the world. The regions with the highest risk of infection are the Mediterranean basin, South and Central America, Eastern Europe, Asia, Africa and the Middle East. Controlling and eradicating it involves high economic costs and complex logistics and advanced veterinary and medical infrastructure. source The lack of resources in developing countries development, where domestic animals are the main source of food, traction and transport, makes the disease a cause of severe economic loss and human suffering.


Vaccination and treatment

There is no humanvaccine for brucellosis. There is a treatment combining several antibiotics, but it is long and expensive and difficult to apply in many areas. The best way to control brucellosis is to reduce or eliminate infection in sick animals. Vaccines are available for this purpose, but they do not provide absolute immunity, and make it difficult to distinguish between vaccinated and infected animals, as their antigens are identical to those of virulent strains.


Lines of research

Brucella escapes early detection by the immune system as it does not possess macromolecules with patron saint molecular associated with tagged pathogens. Thus, before activation of the immune system, the bacterium has adaptive time to reach the interior of certain cells, multiply and generate disease.

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Our work aims to:

(a) to develop new vaccines against ovine and porcine brucellosis.

(b) improving diagnostic tools.

(c) to gain a better understanding of the mechanisms of pathogenicity of the causative agent of brucellosis.

(d) to carry out actions of teaching and international cooperation.

In partnership with the School of Medicine of the University of Navarra, we are taking part in ICONZ - AfricaICONZ - Africa, an international project that aims to improve animal health and production in several countries on the African continent.


Team researcher Bacterial pathologies. Brucellosis


Ignacio Moriyón (PhD)

Co-researcher Main


+34 948 425600 Extension: 806356

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Raquel Conde (PhD)

Principal Investigator


+34 948 425600 Extension: 803393

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Maite Iriarte Cilveti (PhD)

Research fellow


+34 948 425600 Extension: 806524

View CV "View CV of Maite Iriarte Cilveti (PhD)".

Amaia Zúñiga Ripa (PhD)

Research fellow


+34 948 425600 Extension: 806205

View CV "View CV of Amaia Zúñiga Ripa (PhD)".

Miriam Salvador (PhD)

Research fellow


+34 948 425600 Extension: 806205

View CV "View CV of Miriam Salvador (PhD)".


Alberto Delgado

Specialist technician


+34 948 425600 Extension: 806205

View CV "View Alberto Delgado's CV".

Aitor Elizalde

PhD Student


+34 425600 Extension: 806205

Maite Loperena

PhD Student


+34 425600 Extension: 806205

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