Precision nutrition

The lines of research that converge in the area of Precision Nutrition have as main goal the design of new personalised nutritional strategies that allow to improve the prevention and treatment of the main diseases of the 21st century related to diet and lifestyle. In fact, in recent years, the group has developed novel nutritional strategies aimed at obesity, diabetes, non-alcoholic hepatic steatosis and other pathologies related to ageing and inflammation.

Researchers in this line investigate the different factors that contribute to metabolic heterogeneity, including variations in Genetics, epigenetics, the microbiome, lifestyle, dietary intake, psychological factors, physical exercise and environmental exhibition .

To this end, special attention is paid to:

  • Genetic and epigenetic traits, applying NGS sequencing technologies

  • Gut microbiota composition through metagenomics

  • The various phenotypic and metabolic markers, including anthropometric, biochemical and inflammatory markers, as well as the response to stressors

  • Biomarkers of intake and metabolic status, using metabolomics techniques

  • The characteristics of per diem expenses, ration size and eating behaviour and habits, as well as the barriers and facilitators of behavioural change

  • Other subjective and modifiable factors, such as psychological and behavioural, cultural, socio-economic, physical activity, anxiety and stress-related factors.

The integration of all this information, especially the pan-omic data , will reveal the genetic, epigenetic, microbiota, metabolic and psychological profiles responsible for predisposition to various diseases, leading to the development of precision nutrition that will provide the right treatment on an individualised basis.

To this end, algorithms and decision trees are developed to predict the risk of disease incidence, the metabolic response and the individual's ability to adhere to a given dietary treatment. These results allow the development of tools for the individualised diagnosis of nutritional and health status, and the subsequent personalised nutritional recommendation.

On the other hand, it is also goal of this area the research nutritional in vulnerable populations (elderly, children,...) and in special physiological situations (athletes, pregnancy, breastfeeding,...).


Lines of research

This line studies the adaptation and application of tools and technologies for the improvement of eating behaviour (e.g. for portion control and speed of intake), as well as the development, validation and application of new technologies and dietary instruments focused on weight control, improvement of satiety and enhancement of self-control mechanisms in overweight patients.

The aim is to gain a better understanding of the behavioural factors that lead to excessive consumption of energy and certain types of food, in order to develop new strategies for a more successful approach to obesity based on sustainable changes in the patient's eating behaviour. 

The goal of this line is the design of new nutritional strategies based on phenotypic and genotypic profiles, more personalised and with greater fees of success in combating obesity and preventing associated comorbidities.

These strategies include the application of information from omics technologies, which provide knowledge of genetic, metabolic and microbiota characteristics, in order to design more personalised strategies. It also includes the use of new bioactive compounds, probiotics and functional foods, both those developed at the CIN and others from the agri-food and nutraceutical industries.

It also applies aspects related to eating behaviour, chrononutrition, metabolic and psychological profiles, inflammatory and oxidative stress markers, as well as different strategies based on physical exercise, anxiety and stress management, or types of fasting.

goal This line analyses the interactions between Genetics, epigenetics, nutrition, microbiota, metabolism and lifestyle, with the aim of identifying biomarkers related to individual susceptibility to develop obesity and related pathologies, predicting individualised response to different treatments, and identifying new compounds and probiotics that may be useful in the prevention and treatment of these pathologies. The integration of all this information will provide a complete picture of the potential health risks and individual needs of each individual.

The aim of these tools is to design and commercialise tests based on omics technologies that allow for a personalised approach to the disease:

- identify genetic variants (SNPs) associated with susceptibility to various health problems and metabolic response to per diem expenses. 

- quantify methylation at various DNA sites (CpG) associated with inflammation, ageing, metabolic complications and metabolic response.

- characterise faecal microbiota composition, diversity and dysbiosis status.

- identify metabolomic patterns that are associated with particular metabolic risks and responses to different foods or dietary patterns.



reference letter: PID2022-141766OB-I00

Funding Entity: Ministry of Science and Innovation. "Proyectos de Generación de knowledge". Call 2022

researcher Principal: Dr. Fermín Milagro Yoldi / Dr. Paula Aranaz Oroz

The rapid increase in the prevalence of overweight and obesity in Western countries leads to the urgent need to develop alternative therapies against its progression. However, these new therapies should focus on treating those factors involved in the development of metabolic disorders associated with excess weight, such as insulin resistance, inflammation, cardiovascular risk or non-alcoholic fatty liver disease development .

Because of their importance in the homeostatic regulation of energy metabolism, changes in gut microbial proportions or dysbiosis may be related to metabolic alterations present in obesity-related diseases. However, despite significant advances in recent years in the understanding of the role of intestinal microorganisms in the metabolic health of the host, most of the relationships between bacteria in the intestinal tract, as well as the mechanisms by which they exert their beneficial or detrimental functions, are still unknown.

In this sense, an in-depth study of the bacterial metabolites associated with metabolic syndrome-related dysbiosis would allow us to identify the postbiotics that represent a greater or lesser metabolic risk in an individual. This panel of postbiotics could give rise to diagnostic tools to predict the greater or lesser Degree of dysbiosis in a subject, as well as to associate it with the risk of suffering from other metabolic disorders associated with obesity and metabolic syndrome, such as excess adiposity, insulin resistance, fatty liver or inflammation, among others.

On the other hand, the modulation of the human intestinal microbiota through the use of food ingredients with prebiotic activities could be a therapeutic strategy to mitigate the characteristic alterations of the metabolic syndrome, promoting the proliferation of those bacterial species that produce metabolites or postbiotics beneficial to the host due to their antiobesogenic, antidiabetic or anti-inflammatory properties.

This project focuses on generating new knowledge on the role of gut microbiota dysbiosis in the development of obesity, identifying those metabolites of bacterial origin (postbiotics) associated with the different parameters of the metabolic syndrome, together with the assessment of the anti-obesity properties of prebiotics and postbiotics as potential therapy for the prevention of the different metabolic alterations characteristic of obesity.

Different metabolomic, lipidomic and metagenomic analyses will be developed, along with in vitro and in vivo models, including screening in C. elegans, studying mechanisms of action in rodents, and assessment therapeutics in a human intervention study.

Funding Entity: department de Universidad, Innovación y Transformación Digital. Government of Navarra. Grants to Technology Centres and Research Bodies to carry out collaborative research and development projects (call for proposals 2020).

Funding: 272.331,58 €.

researcher main: Eva Almirón Roig

Consortium: University of Navarra, CNTA

Duration: 16/06/2020 - 30/11/2022


Obesity is a global public health problem associated with multiple medical complications and a risk factor for infections such as COVID-19, leading to high public health costs. It is therefore of paramount importance to develop methods to treat overweight and obese people effectively and cost-effectively, especially in the long term deadline. One of the problems core topic of obesity lies in habits that lead to excessive energy consumption, notably the intake of too large portions or portions of starches, fats and sugars, to the detriment of vegetables and legumes. In response to this challenge, as part of two previous projects (PT028 "PORTIONS" and PT008 "PORTIONS-2") our group developed and validated a new portion plate prototype to educate and help overweight people to consume balanced amounts of the different food groups from the per diem expenses. Although the plate was well accepted and confirmed as a promising tool for weight management, it needs to be optimised and further evaluated in the overweight population before being tested in large-scale clinical trials at programs of study . Moreover, the transfer of the concept of "fixed portions" to other contexts, such as ready meals, offers the opportunity to explore the suitability of technologies for future industrial applications, e.g. for the development of new sustainable fixed portion food products and tableware. In addition, an opportunity opens up for the research of other types of tools to support intake monitoring, allowing an estimation of the nutritional and/or caloric value of the dish being consumed. On this basis, the overall goal of PORTIONS-3 is to optimise the design and enhance the impact of fixed portion instruments to improve their effectiveness in overweight people. Moreover, in partnership with the National Centre for Food Technology (CNTA), the suitability of technological strategies for future industrial applications of the concept of balanced portions in other contexts will be explored.

Reference: 0011-1411-2019-000033 Alinfa

Funding Entity: department de development Económico. Government of Navarre. Grants for the implementation of strategic projects of research and development 2019-2021. challenge 4. ALPES. Personalised and Sustainable Food.

researcher Principal: Dr. Santiago Navas-Carretero

Consortium: IRIGOYEN COMEDOR SALUDABLE S.L. (leader), INDUSTRIAS ALIMENTARIAS DE NAVARRA S.A., HARIVENASA S.L., APERITIVOS Y EXTRUSIONADOS S.A., ALIMENTOS SANYGRAN S.L., Centro Nacional de Tecnología y Seguridad Alimentaria (CNTA), University of Navarra (Nutrition Research Centre and UNAV genomic platform), Public University of Navarra (group ALTER).


Childhood overweight and obesity fees are increasing at an alarming rate, with Spain's being one of the highest in Europe. Here, one in five children - between 18 and 21% - are obese or overweight, according to the latest data from the World Health Organisation (WHO). One of the most immediate consequences of childhood obesity is the emergence of children and adolescents with diabetes subject 2, hypercholesterolemia and high blood pressure, which predisposes them to serious cardiovascular diseases from childhood onwards. Excess weight also affects the bones and the locomotor system as a whole, reducing tolerance to physical exercise and causing respiratory problems. Furthermore, it should be borne in mind that being overweight can have a negative effect on the emotional development of children and adolescents, with feelings of inferiority and leave self-esteem. They may also feel rejected and tend to isolate themselves.

There are two main causes for this situation: inadequate diets and sedentary lifestyles. Unfortunately in Spain, the Mediterranean per diem expenses , the nutritional outline that financial aid helps to ward off cancer, fight obesity or prevent cardiovascular diseases, has fallen into disuse. Paradoxically, this Mediterranean per diem expenses is practised more in northern Europe than in southern Europe. Several factors have influenced this situation: lack of time to prepare menus and cook food at home, the economic crisis affecting the shopping basket and price pressure from school canteens, lack of awareness among families of the impact of per diem expenses on health, etc. Thus, Spanish children's diets are currently rich in protein from meat and milk, in free sugars from pastries and sugary drinks, among others, and poor in fruit, vegetables, nuts and pulses.

It is therefore necessary and urgent to reverse this situation and promote to establish healthy eating habits from childhood, and to do so, a number of challenges need to be addressed:

Children's preferences that lead them to accept or reject certain foods. They are both innate and learned and vary considerably with age and experience. Exposure to different tastes at critical periods of development has a profound influence on children's food choices. In addition, children's preferences also reflect their immediate environment. Economic, social, psychological or even environmental factors influence eating.

Lack of knowledge and training on the impact of per diem expenses on children's health.


Diversity of the child population: allergies, intolerances, etc,

The project ALINFA aims to address these challenges, generating knowledge, tools and solutions to improve access to healthy food for children aged 3 to 12, both through school meals and home meals. The project is based on a participatory approach in which children collaborate and participate in the process of creating the developments of project. The knowledge of their tastes and preferences, as well as the knowledge of the factors that influence their preferences, will be basic tools for the development of the project. In addition, special focus will be placed on the transfer of results with the aim of goal facilitating the population's access to the developments of project, maximising their impact.

Acronym: CORALS

researcher principal: Dr. Santiago Navas-Carretero

Funding entity: CIBER-Obn (ISCIII)

Childhood obesity has been recognised by WHO as a priority in the Global Action Plan 2013-2020 for the prevention and control of chronic diseases.

The prevalence of childhood overweight and obesity in Europe is high, with a north-south gradient with a higher prevalence in southern countries. The causes of obesity are multifactorial. The main goal of the present study is to identify risk factors for childhood obesity, as well as to quantify the risk of each of them through a longitudinal cohort of children initially aged 3 to 6 years, which is intended to be followed up for a 10-year average .

As specific objectives, the aim is to:

  1. To assess the associations between perinatal risk factors, socioeconomic, cultural and environmental factors and the risk of developing obesity and its comorbidities;

  2. To assess associations between lifestyles (diet, beverage consumption, physical activity, sedentary lifestyle, sleep) and the risk of developing obesity and its co-morbidities;

  3. To assess the association between genetic polymorphisms, metabolomic and metagenomic profiles (determined by omics techniques) and the development of obesity and its comorbidities.

Registration to enrol your child(ren)

Acronym: SWEET

Call: H2020-SFS-2016-2017

Topic: SFS-40-2017

Grant Agreement: 774293

Funding Entity: European Commission

coordinator: University of Liverpool

researcher Principal in Navarra: Prof. J. Alfredo Martinez


Participant Name

Participant Organisation Name



1. Jason Halford

University of Liverpool (Co-ordinator)



2. Anne Raben

Kobenhavns Universitet


Denmark (DK)

3. Douwina Bosscher

Cargill R&D Centre Europe


Belgium (BE)

4. Alfredo Martinez

University of Navarra


Spain (ES)

5. Edith Feskens

Wageningen University



6. Monique Raats

University of Surrey



7. Euan Woodward

European Association for the Study of Obesity



8. Alain Lebail



France (FR)

9. Graham Finlayson

University of Leeds



10. Yannis Manios

Harokopio University


Greece (GR)

11. Lluis Serra

Private Foundation for Nutritional Research


Spain (ES)

12. Mark Reed

University of Newcastle Upon Tyne



13. George Nychas

Agricultural University of Athens


Greece (GR)

14. LoicBriand

InstitutNational de la RechercheAgronomoique


France (FR)

15. Laetitia Gerbe

Tereos Participations


France (FR)

16. Santiago Ortega



Spain (ES)

17. Martine Laville

CRNH Rhone-Alpes


France (FR)

18. Torsten Sehlinger

Mobile Chamber Experts GmbH


Germany (DE)

19. Ellen Blaak

Universiteit Maastricht


Netherlands (NL)

20. Tony Lam



Switzerland (CH)

21. Helen Claringbould



Netherlands (NL)

22. Marine Boursier

Vitagora Pole


France (FR)

23. Stephane Vidry

International Life Sciences Institute (European Branch)


Belgium (BE)

24. Jasper Scholten

Blonk Milieu Advies BV


Netherlands (NL)

25. Paul Finglas

European Food Information Ress AISBL (EUROFIR)


Belgium (BE)

26. Maurizio Notarfonso



Italy (IT)

27. Fottes Panetsos

Bioiatriki SA


Greece (GR)

28. Clare Llewellyn

University College London



29. Alicja Szofer-Araya

European Clinical Research Infrastructure Network


France (FR)



The SWEET project has been designed to

i) identify and address the barriers and facilitators to the use of sweeteners and sweetness enhancers (S&SEs) and

ii) examine the risks and benefits of using S&SEs to replace sugar in the diet in the contexts of health, obesity, safety and sustainability. Industry experts will integrate technological, health and sweetness databases to provide a platform on which new and emerging S&SEs can be selected for inclusion in food products.

The behavioural and physiological impact of specific S&SEs will be examined in acute and repeated dosing studies and natural population differences (by age, region, gender etc) in sweetness perception established. A sensory profile will be developed and genetic determinants assessed. The core randomised controlled trial will adopt a whole diet approach to examine the impact of prolonged sugar replacement on weight control, appetite and energy intake.

Underlying mechanistic effects of S&SE use, alone and in combination, will be evaluated using the technology platform developed in acute studies.

Outcomes relating to safety and overall health risks will be

i) measured in acute and chronic studies and

ii) investigated in secondary data (long term interventions, prospective cohorts).

The preferences for and perceptions of S&SEs within European consumers, and the barriers to their acceptance, consumption and use will be determined.

The environmental cost and sustainability of replacing sugar with S&SEs will also be modelled. Consumers will be engaged to inform research design, and stakeholder driven exploitation and impact plans will be developed to communicate and disseminate project objectives and results to

i) address the role of sweeteners in weight control for target audiences (consumers, health professions, scientists, policy makers, regulators) and

ii) move effective products nearer to market.

A gender action plan will be developed and implemented to promote equity across all research activities.


Overall objective: To examine the barriers & facilitators to the use of sweeteners & sweetness enhancers (S&SEs) & examine the likely risks & benefits of using them to replace sugar in the diet in the context of health, obesity, safety & sustainability.


1. Select new & emerging S&SEs& blends, & through integration of technological expertise produce a range of innovative S&SE containing products of appeal to distinct demographics (e.g. age, region, gender).

2. Develop a platform of measures (e.g self-report, biological, cognitive, consumer questionnaires), including new tools, to examine the impact of replacing dietary sugar with S&SEs& validate against new urinary biomarker assays.

3. Determine the role of individual differences (both behavioural e.g. eating behaviour traits & biological e.g. taste receptor polymorphisms) in shaping food preferences & consumption patterns of distinct populations, & examine biological mechanisms underpinning these.

4. Assess the short term effect of specific S&SEs & blends & the prolonged impact of a whole diet approach on body weight, health, satiety, microbiota, biobehavioural processes & consumer perspectives & preferences.

5. Synthesise evidence from diverse European longitudinal data sets to examine the relationship between habitual S&SE use & obesity, health & safety in key geographic & demographic cohorts.

6. Examine the economic, environmental & social sustainability of replacing sugar with S&SEs across production, supply, consumption & waste (life cycle sustainability assessment) in the context of global supply chains using project case studies.

7. Assess the potential toxicology, allergencity & safety (microbiological, gastrointestinal (G.I.) side effects, microbiota & other adverse effects) of specific novel S&SE combinations & of the whole diet approach.

8. Review the regulatory barriers to innovation & tailor exploitation plans & dissemination accordingly.

Acronym: FOOD4ME

Reference: 265494 (Grant Agreement)  

researcher principal: Prof. Mike Gibney (coordinator); Prof. J. Alfredo Martínez (Spain) 

Understanding the relationship between food and gene expression may make it possible to design an individualised, healthier and more patient-friendly per diem expenses . Food4Me is a project research project led by European Universities and funded by the European Union's 7th Programme framework investigating all aspects of this field using the web as the method of communication with users. 

More information

This project has received funding from the European Union's 7th Research Programme framework , development and test .   

Acronym: PREVIEW

Reference: 312057 (Grant agreement)

Principal Investigators: Prof. Anne Raben (Coordinator); Prof. J. Alfredo Martínez (Spain)

The project is a large-scale, multinational diabetes prevention study funded by the European Union's 7th Programme framework , Australia's National Health and Medical Research committee , New Zealand's Health Research committee , Canada's Department of Higher Education, Research and Science, and the Cambridge Weight Plan. 

Further information

This project has received funding from the European Union's 7th Research Programme framework , development and test .  

Ref. No: PT028

Funding Entity: department de development Económico. Government of Navarre. Projects of research and development. Call for proposals 2018 Technology Centres. Strategic sector Health (IV).

researcher principal: Dr. Eva Almiron Roig.

Participants: UNIVERSITY OF NAVARRA (Nutrition Research Centre, Personalised Nutrition line), UNIVERSITY OF BRISTOL (Dept. of Experimental Psycology), LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE (Dept. of Medical Statistics), HERBA RICEMILLS S.L., PRECISE PORTIONS NUTRITION LEARNING SYSTEMS.

Duration: 2018-2019.

budget97.725 (32.548 € year one, 65.177 € year two)

One of the problems core topic of obesity lies in eating behaviour, in particular habits that lead to excessive energy consumption among which unbalanced portion consumption stands out. Previous programs of study indicate that fixed portion plates may be an acceptable, potentially effective and economical method for weight control however a solid phase of development and programs of study validation is required to optimise their design and corroborate their effectiveness. The main goal of this project is to develop and validate a new portion plate prototype designed for the Spanish population, using official dietary recommendations and the support of a team multidisciplinary plus state-of-the-art technologies (e.g. eyetracking device), to educate and help overweight people to consume balanced portions, in particular of carbohydrates, proteins and vegetables. The phases of project are:

  1. design of a fixed portion plate prototype adapted to the Mediterranean population, on partnership with international dieticians, psychologists and chemical engineers.

  2. Validation of the prototype in healthy overweight and non-overweight men and women, comparing the effect to that of a conventional plate.

  3. Development and evaluation of a new methodological platform, including the eyetracking device, for the assessment of eating behaviour in humans.

Through this project it is hoped to obtain a product capable of educating and helping overweight people to consume balanced portions, which is acceptable, economical and easy to use, for large-scale application (e.g. through the NHS), as a low-cost tool and reducing the time of contact of the health professional with the patient.

Funding Entity: Government of Navarre Industry

Ref. No: PT008 

Principal Investigator: Eva Almirón Roig

Obesity is a global public health problem associated with multiple co-morbidities and leading to high public health costs. One of its issues core topic lies in eating behaviour, in particular excessive energy consumption, which is closely linked to the consumption of unbalanced portions. In response to this problem, the catering sector has started to market tableware designed to try to reduce calorie content and adjust portions in home recipes, however, most of these instruments lack a theoretical basis and their scientific validity is still doubtful. Based on programs of study pilot in our group in obese British patients using calibrated plates, the project PORTIONS (call for proposals 2018) was proposed in order to develop and validate a prototype fixed portion plate for the Mediterranean population. The main goal was to have a validated tool for personalised, versatile and cost-effective dietary treatment, with the possibility of direct application in the National Health Service and in programs of study of intervention as well as as as tool educational in public health campaigns, pharmacy office and consultancy service nutritional. The second goal was to generate new knowledge on cognitive and physiological processes involved in the control of intake for transfer to industry, e.g. to improve the nutritional composition and packaging of pre-cooked dishes, design of new dietary tools and the development/optimisation of ICTs for lifestyle improvement. During the first year of PORTIONS the prototype has been designed and produced working with an international team and a methodological platform with state-of-the-art technologies has been set up, with which the prototype has been pilot tested and its validation initiated. The proposed objectives for 2019 include fill in validation of the prototype in 94 healthy men and women with and without overweight, comparing the effect to that of a conventional plate; validation of the protocol video coding of data for eyetracking; carrying out quality control of the data collected, and carrying out the pending physiological, psychological and cognitive determinations plus descriptive and advanced statistical analyses. 



Ref: 0011-1365-2021-000224

project financed by the Government of Navarra

partnership between NUCAPS and the University of Navarra's research center in Nutrition

The high prevalence of Diabetes mellitus subject 2 (DM2) and its role as a risk factor in the development of other diseases, make this pathology a public health problem. In addition, patients with DM2 present numerous short and long deadline term complications during their lifetime. Neuropathies, retinopathies, renal involvement, coronary artery disease, peripheral vascular disease, etc., entail a very significant loss of quality of life and a risk of death twice as high as in people without this disease. All this means that this status represents a great social burden and an important health care expense .

In this sense, it would be very useful to be able to act in the moments prior to the development of the disease such as in the status of prediabetes, since according to the most recent data available, the conversion of this status to DM2 is around 18% per year and it has even been shown that these people have an increased risk of cardiovascular disease and even death before developing diabetes. However, achieving changes in lifestyle and habits is truly complex and despite the use of some drugs at this stage of the disease, the problem continues to grow. In this context, the use of zein nanoparticles for the prevention of diabetes development subject 2 is a novel element.

In recent years, zein nanoparticles have been proposed and used as oral delivery systems for drugs and bioactive compounds, demonstrating an important capacity to increase the oral bioavailability of compounds ascribed to group II and group IV of the biopharmaceutical classification system. These empty nanoparticles (without containing any biologically active compound) were recently shown to have a hypoglycemic effect in vivo. These results would be due to the stimulatory effect of zein nanoparticles interacting with L cells in the intestine and inducing the release of GLP-1 (glucagon-like peptide subject 1). This opens the door to the use of natural physiological mechanisms that control glycemic metabolism. The fact that these nanoparticles can reach certain areas of the gastrointestinal tract to specifically induce the secretion of GLP-1 by L cells in the intestine opens the door to the use of natural physiological mechanisms that control glycemic metabolism.

Therefore, the present project aims to validate the previous results obtained in animals, through a nutritional intervention study in humans and to advance in the knowledge of its potential use in the dietary management of prediabetic people and/or people diagnosed with diabetes subject 2.

Specific Objectives:

- To study the evolution of biochemical variables related to glycemic metabolism: Fructosamine, basal glucose, basal insulin, C-peptide and evolution of serum GLP-1 levels after 60 minutes of glucose consumption.

- To evaluate the evolution of biochemical variables related to lipid metabolism: total serum cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides.

- To assess the evolution of variables related to liver function: transaminases (ALT/AST).

- To analyze the evolution of the hemogram.

- To evaluate the evolution of anthropometric variables (weight, height, waist and hip) and body composition (body mass index, fat mass, fat-free mass, muscle mass, water and bone mass), to rule out that the observed changes are due to relevant variations in anthropometric parameters.

- Assess adherence to treatment and adverse events.

In order to achieve the proposed objectives, we propose to carry out a nutritional intervention study in 60 volunteers with prediabetes, according to outline:

This business has received a financial aid co-financed 50% by the European Regional Fund development through the ERDF Operational Program 2014-2020 of Navarra.

Funding Entity: Dept. of development Economic; Government of Navarra.

Call for proposals: "Grants for the realization of strategic projects of research and development: Alps".

reference letter: 0011-1411-2021-000031

Principal Investigator: Fermín Milagro

The overall goal of the study design of Healthy and Sustainable Foods and Ingredients from the application of Economics Circular(ALISSEC) is to evaluate the health effect of a vegetable protein-based smoothie in which fiber and resistant starch are also included.

The 3-week study will be carried out in 40 overweight women and men between 20 and 65 years of age. Two study groups will be established, group control and group under study. The assignment of participants to one or the other study group will be completely random, i.e. neither you nor the researcher decide which group you will belong to. Both groups will receive general nutritional recommendations. In addition, along with the nutritional recommendations, both groups will have to consume a shake that will replace breakfast during the 3 weeks of the intervention.


Funding Entity: Dept. of development Economic; Government of Navarra.

Call for proposals: Grants for the implementation of strategic projects of research and development: Gema.

reference letter: 0011-1411-2021-000106

researcher principal: Antonio Pineda Lucena (CIMA)




Funding entity: research and development collaborative projects, call 2020, Government of Navarra.

reference letter: PC131-132

researcher principal: Fermín Milagro


Research Team


→ Verónica Ciáurriz → Ana Lorente
→ María Zabala
→ Rocío Félix García
→ Adriana Andrés Arija


Naroa Andueza

Begoña de Cuevillas

Ester Diez

Ignacio Goyache

Paola M. Mogna

Ana Luz Tobaruela

Deyan Yavorov

Iñigo Clemente Larramendi. Bioinformatician



Fermín Milagro Yoldi

manager from area

Fermín Milagro Yoldi

C/ Irunlarrea, 1

31008 Pamplona, Spain

+34 948 425600