Ruta de navegación

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Aplicaciones anidadas

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Lines of research:
→ design Galenic, Pharmacokinetics and rational use of drugs.
→ New molecules with biological applicability, programs of study of basic and clinical pharmacology.

The research is, for the most part, within the framework of the doctoral program of Medicines and Health which brings together most of the researchers of department. The different programs of study are articulated through the lines of research of the areas that make up the department.

The research groups registered at department are:
Nanomedicines and Vaccines (NANO-VAC).
→ Mycotoxins (MITOX)
Selenated derivatives as therapeutics against cancer, trypanosomes and other pathologies (SECALE)
Nanomedicines and drug delivery
Drug Discovery, medicinal chemistry, immunotherapies and targeted delivery against kinetoplastid parasites (Chagas and leishmaniasis diseases) (KINETOMED)
Pharmacometrics & Systems Pharmacology

desplegable-investigacion

Study of the presence of 19 mycotoxins in human plasma: levels in healthy and sick donors in Navarra and La Rioja.
PhD student: Beatriz Arce López.
Directors: Elena González Peñas and Elena Lizarraga Pérez.
Defence date: 26/04/2021
grade : A ''cum laude''.
doctorate International: no
University where it was read: University of Navarra

design, synthesis and biological assessment of new imidazole derivatives of instructions of Mannich as potential agents for the treatment of Chagas disease.
PhD student : Iván Beltrán Hortelano
Director: Silvia Pérez Silanes
Defence date: 21/07/2021
grade : A ''cum laude''
doctorate International: yes
University where it was read: University of Navarra

Pharmacokinetics and pharmacodynamics and carbamazepine and its metabolites. Population kinetics
PhD student : Amaya Teresa de Jesús Delgado Latorre
Directors: Azucena Aldaz Pastor and César Vinicio Viteri Torres
Defence date: 30/07/2021
grade : A ''cum laude''
doctorate International: no
University where it was read: Universidad de Navarra

Ezetimibe solid dispersions: development and technological and industrial validation
PhD student : Javier Gurrea Garde
Director: Juan Manuel Irache Garreta
Defence date: 21/10/2021
grade : A ''cum laude''
doctorate International: no
University where it was read: Universidad de Navarra

Development of disease and drug models for rare diseases: Application to Acute Intermittent Porphyria
PhD student : Diego Vera Yunca
Directors: José Ignacio Fernández de Troconiz and Zinnia Patricia Parra Guillén
Defence date: 17/12/2021
grade : A ''cum laude''
doctorate International: yes
University where it was read: University of Navarra

Development of three-dimensional biomaterials containing stem cells and neurotrophic factors for brain repair in Parkinson's disease
PhD student : Pablo Vicente Torres Ortega
Directors: Mª José Blanco Prieto and Elisa Garbayo Atienza
Defence date: 21/12/2021
grade : A ''cum laude''
doctorate International: no
University where it was read: University of Navarra

Combinatorial nanomedicine made of squalenoyl-gemcitabine and edelfosine for the treatment of pediatric cancer
Name of the PhD student: Rodríguez Nogales, Carlos
Directors of thesis : María José Blanco Prieto, Patrick Couvreur
Defence date: 6 March 2020
doctoral program where it was defended: Medicines & Health
Whether or not it has accredited specialization from doctorate European : Yes- doctorate international

Novel tissue engineering strategies for cardiac repair after a myocardial infarction.
PhD student : Saludas Echauri, Laura
Director: María José Blanco Prieto, Co-director: Felipe Luis Prósper Cardoso
Defence date: 21-05-2020
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra

Development of novel selenocompounds as antitumor agents.
PhD student : Ruberte Sánchez, Ana Carolina
Director: María del Carmen Sanmartín Grijalba, Co-director: Daniel Plano Amatriain
Defence date: 30-06-2020
grade : A ''cum laude'' doctorate International: Yes
University where it was read: University of Navarra

Towards improved antileishmanial therapies: delivery issues and application to berberine.
PhD student : Calvo Bacaicoa, Alba
Director: María Socorro Espuelas Millán, Co-Director: Esther Moreno Amatria
Defence date: 25-09-2020
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra

Protein-based nanocarriers for the oral delivery of paclitaxel
PhD student : Morales Gracia, Jorge
Director: Juan Manuel Irache Garreta, Co-director: Maite Agüeros Bazo
Defence date: 14-12-2020
grade : A ''cum laude''
doctorate International: No
doctorate Industrial: Yes
University where it was read: University of Navarra

Prescription in patients with drug allergy: critical analysis of an alert system integrated in the medical record.
PhD student : Luri Fernández de Manzanos, Marta
Director: Ana Ortega Eslava, Co-Director: Gabriel Gastaminza Lasarte
Defence date: 17-12-2020
grade : A ''cum laude''
doctorate International: No
University where it was read: University of Navarra

Design, synthesis, biological evaluation and nanoformulation of novel selenocyanate and diselenide derivatives as leishmanicidal and cytotoxic agents.
PhD student : Etxebeste Mitxeltorena, Mikel
Director: María del Carmen Sanmartín Grijalba, Co-director: María Socorro Espuelas Millán
Defence date: 21-12-2020
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra

Towards improved antileishmanial therapies: delivery issues and application to berberine.
PhD student : Calvo Bacaicoa, Alba
Director: María Socorro Espuelas Millán, Co-Director: Esther Moreno Amatria
Defence date: 25-09-2020
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra

Protein-based nanocarriers for the oral delivery of paclitaxel
PhD student : Morales Gracia, Jorge
Director: Juan Manuel Irache Garreta, Co-director: Maite Agüeros Bazo
Defence date: 14-12-2020
grade : A ''cum laude''
doctorate International: No
doctorate Industrial: Yes
University where it was read: University of Navarra

Prescription in patients with drug allergy: critical analysis of an alert system integrated in the medical record.
PhD student : Luri Fernández de Manzanos, Marta
Director: Ana Ortega Eslava, Co-Director: Gabriel Gastaminza Lasarte
Defence date: 17-12-2020
grade : A ''cum laude''
doctorate International: No
University where it was read: University of Navarra

Design, synthesis, biological evaluation and nanoformulation of novel selenocyanate and diselenide derivatives as leishmanicidal and cytotoxic agents.
PhD student : Etxebeste Mitxeltorena, Mikel
Director: María del Carmen Sanmartín Grijalba, Co-director: María Socorro Espuelas Millán
Defence date: 21-12-2020
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra
University where it was read: University of Navarra

Development and implementation of novel methodologies to improve Pharmacometrics and Systems Pharmacology analysis.
PhD student : Irurzun Arana, Itziar
Director: José Ignacio Fernández de Trocóniz Fernández
Defence date: 01-03-2019
grade : A
doctorate International: Yes
University where it was read: Universidad de Navarra

Systems pharmacology in modelling complex scenarios: opportunities and challenges.
PhD student : Ruiz Cerdá, María Leire
Director: José Ignacio Fernández de Trocóniz Fernández
Defence date: 05-04-2019
grade : A ''cum laude''
doctorate International: No
University where it was read: Universidad de Navarra

Optimisation with PK/PD criteria of meropenem therapy in the critically ill patient. Pharmacoeconomic analysis of results.
PhD student : Idoate Grijalba, Ana Isabel
Director: Azucena Aldaz Pastor, Co-Director: Irene Aquerreta González
Defence date: 16-05-2019
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra

Design, synthesis and biological evaluation of Mannich base-type derivatives as potential agents for the treatment of Chagas disease.
PhD student : Paucar Bernabé, Rocio Valeria
Director: Silvia Pérez Silanes, Co-Director: Elsa Moreno de Viguri
Defence date: 03-06-2019
grade : A ''cum laude''
doctorate International: No
University where it was read: University of Navarra

Optimisation of irinotecan and capecitabine treatments in patients with colorectal cancer based on pharmacokinetic techniques and artificial intelligence.
PhD student : Oyaga Iriarte, Esther
Director: Azucena Aldaz Pastor, Co-Director: Onintza Sayar Beristain
Defence date: 27-06-2019
grade : A ''cum laude''
doctorate International: No
doctorate Industrial: Yes
University where it was read: University of Navarra

Application and development of computational approaches to optimise treatment of malignancies using routine clinical data.
PhD student : Pérez Solans, Belén
Director: José Ignacio Fernández de Trocóniz Fernández, Co-director: Marta Santisteban Eslava Defence date: 05-07-2019
grade : A ''cum laude''
doctorate International: Yes
University where it was read: University of Navarra

Towards Mechanistic characterization of Inflammatory Bowel Disease and complicated Urinary Tract Infection using Systems Pharmacology approaches.
PhD student : Balbás Martínez, Violeta
Director: José Ignacio Fernández de Trocóniz Fernández
Defence date: 13-12-2019
grade : A ''cum laude''
doctorate International: Yes
University where it was read: Universidad de Navarra


EQUIPMENT DEPT. PHARMACEUTICAL TECHNOLOGY AND CHEMISTRY  

subject of equipment

model

Brand

Particle analyser 

Malvern 

Mastersizer MSS 

Particle analyser 

Malvern

Nanosight NS300

Particle analyser 

Malvern

Zetasizer Nano ZS 

Particle analyser

Brookhaven  

Zeta Plus 

Laminar flow cabinet 

Indelab 

INDL-95B 

Differential Scanning Calorimeter 

Pyris 

Diamond 

Cryostat 

Leica 

CM1900 

Thin layer chromatograph-MS 

Avilon 

Expression CMS 

Gas Chromatograph-Mass Spectrometer 

Agilent Technologies 

7890A 

Liquid chromatograph -DAD 

Agilent Technologies 

1200 Series 

Ultra-high resolution liquid chromatograph-MS 

Waters 

Acquity UPLC

Liquid chromatograph-DAD 

Waters 

2695 

Liquid chromatograph-DAD-DLS 

Agilent Technologies 

1100 Series 

Liquid Chromatograph-DAD-FDA 

Agilent Technologies 

1100 Series 

Liquid Chromatograph-DAD-FDA 

Agilent Technologies 

1200

Liquid Chromatograph-MS QQQ 

Agilent Technologies 

1200-6410 

TOF-liquid chromatograph 

Agilent Technologies 

1200-6200 

Durometer 

Erweka 

TB24 

Spectrophotometer Impact masses Agilent Technologies 5973 Network
UV-Vis spectrophotometer Agilent Technologies 8453
UV-Vis spectrophotometer plates BioTek PowerWave TS

Compressing machine 

J.Bonals 

B30

Melting point microscope 

Olympus

BH-2 

Fluorescence microscope 

Leica 

BMIL LED FLEXACAMC1 

Polarimeter 

Jasco 

P-1020 

Melting point block 

Büchi 

B540 

Nuclear Magnetic Resonance 

MRI-Bruker 

ADVANCE NEO 400 

Spray Dryer 

Büchi  

Mini Spray Dryer B-290 

Fluorimeter Plates

Tecan

GENios Spectrafluor Plus

Friabilimeter 

Erweka 

TAP

Luminometer tubes 

Berthold 

Sirius Luminomether 

CO2 Incubator 

Scientific Form 

3121 

Freeze dryer 

Telstar 

LyoBeta Mini