ARTI-UP
ARTIchoke by-products as rich source of bioavailable Hydroxycinnamic acids: Disentangling their potential in type 2 diabetes risk reduction through UPcycling strategies and a multi-omics approach (ARTI-UP).
♦ researcher manager : Iziar Amaia Ludwig Sanz-Orrio (IP1) y Sonia García Calzón (IP2)
♦ Funding Entity: Agencia Estatal de research. Ministry of Science, Innovation and Universities.
♦ ♦ subject of call: knowledge Generation Projects 2023. research Oriented subject A
♦ ♦ reference letter of project: PID2023-146251OA-I00
♦ Participating entities:University of Navarra. research center in Nutrition.
♦ Duration: From September 2024 to September 2028.
♦ Amount of subsidy: 262,500 euros.
♦ issue of participants: 7.
Abstract:
Nearly 80% of the artichoke plant is disposed of as by-products or used for animal feed. These by-products may be a rich source of polyphenols, specifically hydroxycinnamic acids (HCA), which could be used through revalorization strategies to increase dietary intake of these bioactive compounds. programs of study epidemiological suggest beneficial effects of dietary HCA intake in reducing the risk of diabetes subject 2. Thus, artichokes could be an interesting dietary source of HCAs with a potential health benefit for overweight people with insulin resistance, who are at high risk of developing diabetes subject 2, and for whom new dietary approaches for diabetes prevention need to be implemented.
The overall goal of project ARTI-UP is to intelligently design an artichoke product from by-products with a high content of bioavailable HCA, capable of being used in healthy and sustainable dietary strategies to prevent diabetes subject 2 in high-risk individuals through the use of a multi-integrating approach omics.
