The high school Higher School of Secretarial and Administrative Studies of the University of Navarra (ISSA) opened its doors in San Sebastian on October 1, 1963. It was installed in the Eva Enea building (on Cuesta de Aldapeta), under the direction of María Luisa González. Two years earlier, Tecnun-Escuela de Ingeniería had also been set up in San Sebastian.

In 1966, ISSA inaugurated the laboratory de Idiomas.

That same year, the first graduating class of management secretaries completed their studies at programs of study .

In 1968, two new curricula were introduced: "Stenotypist and Interpreter" and "Interpreter of business".

In 1970, the evening programs of study "Secretarial Administration" for professionals was introduced. In total, that year, 160 students shared the classrooms of the ISSA building.

ISSA signed, in 1986, the first agreements for exchange students with the ESBI School of the Catholic University of Lille. International internship programs were also established with high school BERNOM in Bordeaux (France) and high school PIHO in Ghent (Belgium).

In 1988 ISSA celebrated its 25th anniversary. After the graduation of the 23rd class, the number of 1,150 graduates reached 1,150 alumni. The placement rate was 100%.

In 1989 ISSA was a founding member of SPACE, the first European network of schools of Modern Languages, Business Administration and International Business.

Until the change in its Study program in 2021, it was part of the organization together with more than 90 institutions of Education .

In 1996, ISSA was a pioneer in the University in having its students participate in the Erasmus Program.

ISSA signed an agreement with the State University of New York in 2001, agreement . Graduates could obtain an Associate Degree, internships and programs of study at the Rochester Institute of Technology.

In 2005 ISSA implemented a new Study program called 'Multilingual Management Assistant' which entailed studying 60% of the degree program in other languages, mainly in English.

In 2009, ISSA's programs of study became an official university Degree , subject to the Bologna plan, combining training with a clear international projection. The Degree in attendance Management-Management Assistance begins to be offered.

ISSA signed, in 2012, student exchange agreements with Centennial College (Canada) and the University of California (Riverside, USA).

In 2013, ISSA moved to Pamplona.

Despite the move to campus in Pamplona, students who had started their programs of study in San Sebastian continued to receive their classes there. The first class to graduate in Pamplona did so in 2017.

That same academic year, 2013-2014, the School celebrated its 50th anniversary with various events. The finishing touch was put with the congress 'The next 50 years at business: challenge and growth staff in a globalized world'.

In 2018, a change was initiated in the Study program, guided by the evolution of the profiles demanded by the business. The new plan, in which the methodology professor by projects was implemented, was bilingual and included two international stays.

In September 2021 ISSA began teaching the Degree in management Applied-Applied Management, the result of the evolution initiated in 2018. The new Degree, unique in Spain, is characterized by its versatility and transversality.

With the profound revision of Study program, ISSA defined, also in 2021, a new name for the center, which was renamed "ISSA School of Applied Management".

Since 1963, the academic and educational proposal of ISSA School of Applied Management has adapted to the needs of business. After a thorough revision of its Study program, today its classrooms train experts in management and organization, with a command of languages and communication skills.