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Biomedical research and personalised medicine in heart failure

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Biomedical research and personalised medicine in heart failure

seminar from group Science, Reason and Faith.
María de Ujué Moreno. Pamplona, September 15, 2020

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María de Ujué Moreno has a degree in Biochemistry and a PhD in Cell and Molecular Biology from the University of Navarra. After a postdoctoral stay at the BHF-Glasgow Cardiovascular Research Centre, she joined the Cardiovascular Disease Program at CIMA. In the laboratory of Myocardial Remodeling and Heart Failure he investigates the molecular and cellular instructions of the myocardial alterations that underlie heart failure, to identify mechanisms that allow early diagnosis and specific, effective and safe treatment of this pathology. She is a member of group of research BIOMARCS of the University of Navarra and of research center Biomédica en network Cardiovascular. She is the author of more than 40 indexed articles and collaborates in national and European research projects. She is a collaborating professor at School de Ciencias.

summary

Heart failure constitutes a medical need that presents difficulties of care due to its increasing prevalence, poor prognosis and expense partner /healthcare. Moreover, its diagnosis and treatment are far from being personalized and precise as in the case of other diseases such as cancer, which is partly due to the inherent limitations of cardiac research . By means of examples from the research developed in the laboratory of Myocardial Remodeling and Heart Failure of CIMA we will review various approaches of research in the current scientific context. We will also attend to the ethical implications of such a common scenario in this subject research.