Achieving breakthrough discoveries in medicine requires changes in academia, investor behavior and government policy.

Bringing the patient's problems to laboratory in order to return to the patient solutions that lead to an improvement in the clinical internship is an essential activity for medical progress. The university hospital plays a crucial role in this. With the overflowing accumulation of knowledge and the growing specialization, therapeutic innovation requires the creation of research institutes dedicated to the study of defined areas of human pathology, formed by multidisciplinary groups of qualified researchers acting synergistically. This requires generous long-term funding deadline that cannot be covered by government grants alone.

To achieve breakthrough discoveries in medicine, a change is needed in the operating schemes of the university, in the behavior of investors and in government policy. The university must integrate the university hospital and Schools of Medicine, Pharmacy, Biology, Chemistry and Biochemistry into a common body whose purpose is to research disease and search for new therapies. The university must also establish a new relationship with business and private investors. The latter must support the university center of research from its beginnings, betting in the long term deadline on a harvest of patents that will give rise to entrepreneurial initiatives. The University-business union favors both agents, and also benefits patients and the country's Economics .

The investor/business sector must respect the academic style of freedom in scientific research, while at the same time researchers must not lose sight of the applicability of their findings. This is not a limitation but a stimulus, since there is no greater satisfaction than seeing one's own discoveries become a remedy for the disease. In this new paradigm, private investment sustains the academic center and benefits from its patents, with which it creates business activity and thus wealth and skilled work jobs.

The field of human intelligence is very fertile and the government must know how to nurture the dynamic that makes business spring from the sources of research. This requires the Administration to support a policy of strong tax relief for investments that support applied research centers with a proven capacity to produce useful and exploitable patents. On the other hand, it would be advisable to subsidize in a differential way those universities that contribute in this way to the renewal of the national productive fabric, which is in such great need of change.