Felipe Prosper Cardoso,, director of the area of Cell Therapy of the University of Navarra.
Significant progress
The research carried out by the Oregon scientists is undoubtedly a very significant advance, since it demonstrates for the first time the possibility of generating human embryonic cells from nuclear transfer. There is no doubt that it is also the first step, necessary and essential, to be able to carry out reproductive cloning in humans, i.e. to generate a clone of a person. From the point of view of the application in the field of Cell Therapy, although the technology developed would make it possible to generate embryonic cells specific to each patient, thanks to the discoveries of the award Nobel Prize in Medicine Shynia Yamanaka, this possibility has already existed for six years without the need for nuclear transfer, thanks to the possibility of reprogramming cells using cheaper and more robust systems. In fact, Yamanaka's group is currently making significant progress towards the possibility of therapeutically applying induced reprogrammed cells.
The finding of human nuclear transfer may in turn have repercussions from the point of view of better understanding the reprogramming processes and mechanisms governing embryonic cells. But this strategy, as a way of obtaining cells on demand, is undoubtedly more expensive than cell reprogramming using factors, i.e. the one that won Yamanaka the Nobel Prize. The ethical implications of nuclear transfer in humans are also a key issue, as scientists are almost unanimously against reproductive cloning, i.e. the generation of human clones.