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The Spanish Society of Thrombosis and Hemostasis has awarded the award for the best oral communication in the field of hemorrhage to a research of the research center Médica Aplicada (CIMA) and the Clínica Universidad de Navarra. The award was awarded during the national congress of the scientific society, held in Madrid.

Hemorrhage is an important complication of surgery or trauma. It often requires blood transfusions, which lead to high morbidity and mortality and high health care costs. Researchers at the University of Navarra found in a previous study that metalloproteases (MMPs) play an important role in fibrinolysis or dissolution of blood clots. "In this work we have discovered and characterized a new molecule (CM-352) that inhibits fibrinolysis and reduces blood loss through a new mechanism of action," explains Dr. Josune Orbe, researcher at CIMA and manager of the study, in which researchers from Experimental Hepatology and the Small Molecule Platform at CIMA, as well as Dr. José Antonio Páramo, co-director of the department of Hematology at Clínica Universidad de Navarra.

This preclinical study may form the basis for the employment of this agent in different medical or surgical conditions, with the goal to control bleeding and reduce blood transfusions.