The Institute of Nutrition and Health identifies treatment options for patients with breast cancer and obesity

The Institute of Nutrition and Health (INS) at the University of Navarra held a seminar the Relationship Between Obesity and Breast Cancer: Novel Therapeutic Targets in the Microenvironment,” a meeting focused on the impact of the metabolic and inflammatory context on this disease.

The session, which took place at the Clínica Universidad de Navarra, was given by Dr. Miguel Burgos Lozano, researcher Center for Nutrition Research from the University of Navarra, who presented two of the work areas his team work . First, the project ONCOBEGLUT, which investigates whether the insulin-sensitive glucose transporter GLUT12 is expressed at higher levels in tumors from obese patients. And, secondly, the project RESOLVES investigates how inflammation associated with obesity may influence cancer and how controlling it could help reduce its effects.

Within the framework , Dr. Burgos explained that obesity “is not merely an excessive accumulation of adipose tissue,” but that this tissue can become altered and begin to function differently, triggering metabolic and inflammatory changes that may influence the progression of breast cancer. In this regard, he noted that the fatty tissue surrounding the tumor is not merely an accessory but can actually promote its growth. “Tumor cells are very glucose-hungry,” he stated, explaining that this line of research how the metabolic context associated with obesity can facilitate entrance tumor cells and influence their progression.

For its part, RESOLBE focuses on studying Degree chronic inflammation Degree with obesity and its role in breast cancer. The research whether promoting the active resolution of inflammation could help improve the tissue microenvironment and limit some of the processes that promote tumor growth.

The seminar approximately 50 clinical professionals, researchers, faculty members, and students from the Schools Pharmacy and Nutrition and Medicine who were interested in gaining a deeper understanding of the biological mechanisms linking obesity to the development progression of breast cancer. The session highlighted the importance of approaching the disease from a metabolic and inflammatory perspective and of integrating these factors into research future clinical practice.